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      Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices.

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      Lab on a chip

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          Abstract

          A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-aminopropyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS "glue" or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.

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          Author and article information

          Journal
          Lab Chip
          Lab on a chip
          1473-0197
          1473-0189
          Mar 7 2010
          : 10
          : 5
          Affiliations
          [1 ] Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA.
          Article
          NIHMS714643
          10.1039/b924816a
          4538600
          20162227
          3b83ab7d-cf00-440f-8a91-57f2dae0553a
          History

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