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      Relationship Between Changes in the Temporal Dynamics of the Blood-Oxygen-Level-Dependent Signal and Hypoperfusion in Acute Ischemic Stroke.

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          Abstract

          Changes in the blood-oxygen-level-dependent (BOLD) signal provide a noninvasive measure of blood flow, but a detailed comparison with established perfusion parameters in acute stroke is lacking. We investigated the relationship between BOLD signal temporal delay and dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) in stroke patients.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Stroke
          Title: Stroke
          Publisher: Ovid Technologies (Wolters Kluwer Health)
          ISSN (Electronic): 1524-4628
          ISSN (Print): 0039-2499
          Publication date (Electronic): Apr 2017
          Volume: 48
          Issue: 4
          Affiliations
          [1 ] From the Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Germany (A.A.K., A.-C.O., R.G., H.J.A., K.V., J.B.F.); Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (A.A.K., T.N., A.V.); Mind, Brain, Body Institute, Berlin School of Mind and Brain, Humboldt-University, Berlin, Germany (A.A.K., A.V.); and Center for Cognitive Neuroscience Berlin (CCNB), Department of Education and Psychology, Freie Universität Berlin, Germany (T.N.). ahmed-abdelrahim.khalil@charite.de.
          [2 ] From the Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Germany (A.A.K., A.-C.O., R.G., H.J.A., K.V., J.B.F.); Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (A.A.K., T.N., A.V.); Mind, Brain, Body Institute, Berlin School of Mind and Brain, Humboldt-University, Berlin, Germany (A.A.K., A.V.); and Center for Cognitive Neuroscience Berlin (CCNB), Department of Education and Psychology, Freie Universität Berlin, Germany (T.N.).
          Article
          Publisher Item ID: STROKEAHA.116.015566
          DOI: 10.1161/STROKEAHA.116.015566
          PubMed ID: 28275197
          SO-VID: 3baa8002-b9c4-4f16-8dc1-e13c528a65fe
          History

          Keywords: perfusion imaging,brain,gadolinium,blood volume,stroke,BOLD delay
          Data availability:
          Keywords: perfusion imaging, brain, gadolinium, blood volume, stroke, BOLD delay

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