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Clinicopathologic aspects of 8 Kaposi's sarcomas among 1009 renal transplant patients.

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      Abstract

      In 8 of 1009 patients receiving renal grafts and consecutive immunosuppressive therapy during the last 20 years in Budapest, Hungary, Kaposi's sarcoma developed 6.5 months (average) after transplantation. Of 8 cutaneous cases of this disease, 5 also presented visceral manifestations. Seven patients died. Those with visceral tumors died because of the tumor itself. One patient affected by cutaneous tumor has survived for 5 years post-treatment. The relatively high incidence of Kaposi's sarcoma may be explained by a high infection rate with Herpes virus 8, which was shown to be positive in all three cases investigated.

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      Author and article information

      Affiliations
      [1 ] 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University Medical School, Budapest, Hungary. bszende@korb1.sote.hu
      Journal
      Gen Diagn Pathol
      General & diagnostic pathology
      0947-823X
      0947-823X
      Dec 1997
      : 143
      : 4
      9489952

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