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      Exercise Testing and Indirect Assessment of Myocardial Oxygen Consumption in Evaluation of Angina Pectoris

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          Abstract

          Exercise testing is an important means of evaluating the patient with angina pectoris, providing objective data not available from conventional clinical assessment. In utilizing exercise to determine functional impairment in angina, it is essential to distinguish between external stress, or the load on the skeletal muscles, and internal or cardiac stress. Evaluation of external exercise capacity alone is limited as a measure of cardiac performance since the relationship between external function and cardiac performance is not necessarily direct. A readily applicable approach to determination of cardaic capacity in angina is afforded by indirect assessment of myocardial oxygen consumption (MVO<sub>2</sub>). This is achieved through derived indexes utilizing heart rate and blood pressure, two major determinants of MVO<sub>2</sub>, in the form of the product of heart rate and systolic blood pressure. Although this approach does not encompass all the major determinants of MVO<sub>2</sub>, changes in the heart rate-blood pressure product bear a close correlation to alterations in directly measured MVO<sub>2</sub>. Within limits and employed with caution, indirect assessment of MVO<sub>2</sub> is useful in elucidating mechanisms of action of extracardiac and intrinsic myocardial factors in the provocation and therapy of angina pectoris.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          978-3-8055-2805-4
          978-3-318-02029-8
          0008-6312
          1421-9751
          1977
          1977
          31 October 2008
          : 62
          : 3
          : 174-189
          Affiliations
          Section of Cardiovascular Medicine, Departments of Medicine and Physiology, University of California, School of Medicine, Davis and Sacramento, Calif.
          Article
          169852 Cardiology 1977;62:174–189
          10.1159/000169852
          408007
          © 1977 S. Karger AG, Basel

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          Page count
          Pages: 16
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