Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
8
March
2017
Publication date Collection: 2017
Volume: 12
Issue: 3
Electronic Location Identifier: e0171552
Affiliations
[1
]Department of Neurology, Friedrich-Alexander-University, Erlangen-Nuremberg, Germany
[2
]Department of Molecular Neurology, Friedrich-Alexander-University, Erlangen-Nuremberg,
Germany
[3
]Institute of Molecular Neurobiology, Ruhr-University, Bochum, Germany
Heinrich-Heine-Universitat Dusseldorf, GERMANY
Author notes
Competing Interests: Fingolimod is a product of Novartis. There are no other patents, products in development
or marketed products to declare. This does not alter our adherence to all the PLOS
ONE policies on sharing data and materials.
-
Conceptualization: D-HL AM AW SW JW RAL.
-
Formal analysis: D-HL KH LB CR JS AK RAL.
-
Funding acquisition: SW JW RAL.
-
Investigation: D-HL SS KH LB CR AK.
-
Methodology: D-HL SS SW JW RAL.
-
Project administration: D-HL RAL.
-
Resources: JS AK AM SW JW.
-
Supervision: D-HL AM SW JW RAL.
-
-
-
Writing – original draft: D-HL SS AW JS SW JW RAL.
-
Writing – review & editing: D-HL RAL.
Article
Publisher ID:
PONE-D-16-18937
DOI: 10.1371/journal.pone.0171552
PMC ID: 5342171
PubMed ID: 28273090
SO-VID: 3be7e2fd-e393-411b-ae29-6a97d0bdd182
Copyright © © 2017 Lee et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award Recipient
:
Jürgen Winkler
The microscope used in this study was funded by the Deutsche Forschungsgemeinschaft
(DFG). Novartis Pharma Germany supported previous research on fingolimod and provided
fingolimod-1 phosphate for the present study. The funders had no role in the study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Glial Cells
Subject:
Macroglial Cells
Subject:
Astrocytes
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Neurochemistry
Subject:
Neurotransmitters
Subject:
Glutamate
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neurochemistry
Subject:
Neurotransmitters
Subject:
Glutamate
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Neuroanatomy
Subject:
Spinal Cord
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Neuroanatomy
Subject:
Spinal Cord
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neuroanatomy
Subject:
Spinal Cord
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Central Nervous System
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Central Nervous System
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Demyelinating Disorders
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Neurodegenerative Diseases
Subject:
Multiple Sclerosis
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Neurons
Subject:
Neuronal Dendrites
Subject:
Neurites
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Cellular Neuroscience
Subject:
Neurons
Subject:
Neuronal Dendrites
Subject:
Neurites
Subject:
Research and Analysis Methods
Subject:
Biological Cultures
Subject:
Cell Cultures