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      Stress measurement using speech: Recent advancements, validation issues, and ethical and privacy considerations

      1 , 2 , 2
      Stress
      Informa UK Limited

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          Abstract

          Life stress is a well-established risk factor for a variety ofmental and physical health problems, including anxiety disorders, depression, chronic pain, heart disease, asthma, autoimmune diseases, and neurodegenerative disorders.The purpose of this article is to describe emerging approaches for assessing stress using speech, which we do by reviewing the methodological advantages ofthese digital health tools, and thevalidation, ethical, and privacy issues raised bythese technologies.As we describe, itis now possible to assess stress via the speech signalusing smartphones and smart speakers that employ software programs and artificial intelligence to analyze several features of speech and speech acoustics, including pitch, jitter, energy, rate, and length and number of pauses.Because these digital devices are ubiquitous, we can nowassess individuals’ stress levels in real time in almost any natural environment in which people speak.These technologies thus have great potential for advancing digital health initiatives that involve continuously monitoring changes in psychosocial functioning and disease risk over time. However, speech-based indices of stress have yet to bewell-validated against stressbiomarkers (e.g., cortisol, cytokines) that predict disease risk. In addition, acquiringspeech samplesraises the possibility thatconversations intended to be private could one day bemade public; moreover, obtaining real-time psychosocial risk information prompts ethical questions regarding how these data should be used for medical, commercial, and personal purposes. Althoughassessing stress using speech has enormous potential, there are critical validation, privacy, and ethical issues that must be addressed.

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          Most cited references30

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          Is Open Access

          More than a feeling: A unified view of stress measurement for population science

          Stress can influence health throughout the lifespan, yet there is little agreement about what types and aspects of stress matter most for human health and disease. This is in part because “stress” is not a monolithic concept but rather, an emergent process that involves interactions between individual and environmental factors, historical and current events, allostatic states, and psychological and physiological reactivity. Many of these processes alone have been labeled as “stress.” Stress science would be further advanced if researchers adopted a common conceptual model that incorporates epidemiological, affective, and psychophysiological perspectives, with more precise language for describing stress measures. We articulate an integrative working model, highlighting how stressor exposures across the life course influence habitual responding and stress reactivity, and how health behaviors interact with stress. We offer a Stress Typology articulating timescales for stress measurement – acute, event-based, daily, and chronic – and more precise language for dimensions of stress measurement.
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            Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model.

            This study examined whether chronic stress impairs the immune system's capacity to respond to hormonal signals that terminate inflammation. Fifty healthy adults were studied; half were parents of cancer patients, and half were parents of healthy children. Parents of cancer patients reported more psychological distress than parents of healthy children. They also had flatter diurnal slopes of cortisol secretion, primarily because of reduced output during the morning hours. There was also evidence that chronic stress impaired the immune system's response to anti-inflammatory signals: The capacity of a synthetic glucocorticoid hormone to suppress in vitro production of the pro-inflammatory cytokine interleukin-6 was diminished among parents of cancer patients. Findings suggest a novel pathway by which chronic stress might alter the course of inflammatory disease.
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              Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test.

              Validated biological and psychological markers of acute stress in humans are an important tool in translational research. The Trier Social Stress Test (TSST), involving public interview and mental arithmetic performance, is among the most popular methods of inducing acute stress in experimental settings, and reliably increases hypothalamic-pituitary-adrenal axis activation. However, although much research has focused on HPA axis activity, the TSST also affects the sympathetic-adrenal-medullary system, the immune system, cardiovascular outputs, gastric function and cognition. We critically assess the utility of different biological and psychological markers, with guidance for future research, and discuss factors which can moderate TSST effects. We outline the effects of the TSST in stress-related disorders, and if these responses can be abrogated by pharmacological and psychological treatments. Modified TSST protocols are discussed, and the TSST is compared to alternative methods of inducing acute stress. Our analysis suggests that multiple readouts are necessary to derive maximum information; this strategy will enhance our understanding of the psychobiology of stress and provide the means to assess novel therapeutic agents. Copyright © 2013 Elsevier Ltd. All rights reserved.
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                Author and article information

                Journal
                Stress
                Stress
                Informa UK Limited
                1025-3890
                1607-8888
                April 04 2019
                July 04 2019
                April 04 2019
                July 04 2019
                : 22
                : 4
                : 408-413
                Affiliations
                [1 ] Cousins Center for Psychoneuroimmunology and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA;
                [2 ] Affective Computing Group, MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA
                Article
                10.1080/10253890.2019.1584180
                7081839
                30945584
                3c050bc0-e5e5-4d68-867f-084d869b19cd
                © 2019
                History

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