67
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Emphysematous cholecystitis presenting as gas-forming liver abscess and pneumoperitoneum in a dialysis patient: a case report and review of the literature

      case-report

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background

          Emphysematous cholecystitis is a rare variant of acute cholecystitis with a high mortality rate. The combination of emphysematous cholecystitis, liver abscess and pneumoperitoneum are even rarer. Herein we present a case of emphysematous cholecystitis in a senile diabetic lady who had worsening hemodynamics while undergoing hemodialysis.

          Case presentation

          A 64-year-old woman with history of type 2 diabetes mellitus and end stage renal disease with regular hemodialysis presented to the emergency department with a 1-day history of sudden onset of lassitude and hypotension during hemodialysis. The result of a computed tomography (CT)-scan revealed air encircling the gallbladder, liver parenchymal and minimal pneumoperitoneal and liver abscess with no cholelithiasis. The patient had received empirical antibiotics with piperacillin-tazobactam 2.25 g intravenous route every 6 h for 14 days and cholecystectomy with surgical debridement and lead an uneventful postoperative hospital course. Escherichia coli was demonstrated as well as blood culture and peritoneal fluid culture.

          Conclusion

          In a senile diabetic and dialysis patient, we should take emphysematous cholecystitis into consideration once vague abdominal pain occurrs. Empirical antibiotic therapy and adequate surgical intervention should take place as soon as possible.

          Related collections

          Most cited references37

          • Record: found
          • Abstract: found
          • Article: not found

          Gut bacterial translocation may aggravate microinflammation in hemodialysis patients.

          Bacterial translocation (BT) promotes microinflammation in predialysis patients with end-stage renal disease (ESRD). However, the change in BT has not been reported in ESRD patients undergoing regular hemodialysis treatment. The present study investigated whether hemodialysis promotes gut BT and microinflammation.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Recurrent circulatory stress: the dark side of dialysis.

            Current conventional hemodialysis (HD) is largely an industrialized process, with inadequate attention to the role that the dialysis treatment itself may play in the development and promulgation of uremic related disease states. HD is capable of exerting significant recurrent systemic circulatory stress. There is already an appreciation that this may be important in the development of cardiac disease, but it appears that this systemic insult is capable of resulting in perfusion-dependent injury of a wide range of vulnerable vascular beds. These include gut, brain, and potentially the kidney. This predominantly hemodynamic injury can therefore result a mixed picture of direct perfusion-related injury, local/systemic inflammation, and potentiation of further cycles of injury. This article aims to put forward a pathophysiological paradigm that places dialysis-induced acute injury at the center of much of the observed disease burden in HD patients. © 2010 Wiley Periodicals, Inc.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Emphysematous cholecystitis with massive gas in the abdominal cavity.

              Emphysematous cholecystitis is a rare variant of acute cholecystitis with a high mortality rate. The combination of emphysematous cholecystitis and pneumoperitoneum is also rare. We herein describe a case of emphysematous cholecystitis with massive gas in the abdominal cavity. A 77-year-old male presented with epigastric pain and lassitude lasting for one week. A computed tomography scan demonstrated massive gas in the abdominal cavity. Gas was also detectable inside the gallbladder. Massive ascites as well as a pleural effusion were also detected. Under the diagnosis of perforation of the digestive tract, we performed emergency surgery. Beyond our expectations, the perforation site was not in the alimentary tract, but rather in the gallbladder. We then diagnosed the patient with emphysematous cholecystitis with perforation, and performed cholecystectomy. A pathological examination of the resected gallbladder revealed necrosis in the mucosa and thinning of the wall. Cultures of the ascites detected Clostridium perfringens, a gas-producing microorganism.
                Bookmark

                Author and article information

                Contributors
                ericliao0217@gmail.com
                chi12017@gmail.com
                wuhsienku@gmail.com
                benrjbridge@gmail.com
                knnonn@yahoo.com.tw
                tsgh11@gmail.com
                modern0827@gmail.com
                hiliangu1204@yahoo.com
                ndmcndmcndmc@gmail.com
                nephrooil@gmail.com
                chienstkl@gmail.com
                +886-07-7490633 , +886-0929674696 , tmk802@gmail.com
                Journal
                BMC Nephrol
                BMC Nephrol
                BMC Nephrology
                BioMed Central (London )
                1471-2369
                1 March 2016
                1 March 2016
                2016
                : 17
                : 23
                Affiliations
                [ ]Department of Medicine, Kaohsiung Armed Forces General Hospital, No.2, Zhongzheng 1st Rd, Lingya Dist, Kaohsiung City, 802 Taiwan R.O.C
                [ ]Department of Pathology, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan R.O.C
                [ ]Department of Internal medicine, Division of Nephrology, Tri-service general hospital, National defense Medical center, No.325, Section 2, Cheng-Kung Road, Neihu 114, Taipei, Taiwan R.O.C
                Author information
                http://orcid.org/0000-0003-4156-0912
                Article
                237
                10.1186/s12882-016-0237-3
                4774179
                26932814
                3c5cead1-dab6-41e7-8b3a-921afe6764cc
                © Liao et al. 2016

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 12 August 2015
                : 19 February 2016
                Categories
                Case Report
                Custom metadata
                © The Author(s) 2016

                Nephrology
                emphysematous cholecystitis,gas-forming liver abscess,pneumoperitoneum,dialysis
                Nephrology
                emphysematous cholecystitis, gas-forming liver abscess, pneumoperitoneum, dialysis

                Comments

                Comment on this article