Contributors
Leticia Zarantonelli: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: ValidationRole: Writing – original draftRole: Writing – review &
editing
Alejandra Suanes: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: ValidationRole: Writing – review & editing
Paulina Meny: Role: InvestigationRole: MethodologyRole: Resources
Florencia Buroni: Role: Data curationRole: InvestigationRole: MethodologyRole: Resources
Cecilia Nieves: Role: Data curationRole: Formal analysisRole: InvestigationRole: Methodology
Ximena Salaberry: Role: InvestigationRole: MethodologyRole: Resources
Carolina Briano: Role: Investigation
Natalia Ashfield: Role: Methodology
Caroline Da Silva Silveira: Role: Investigation
Fernando Dutra: Role: ResourcesRole: Supervision
Cristina Easton: Role: MethodologyRole: Resources
Martin Fraga:
ORCID: http://orcid.org/0000-0003-3390-9723
Role: InvestigationRole: Writing – review & editing
Federico Giannitti:
ORCID: http://orcid.org/0000-0001-8799-6848
Role: ResourcesRole: Writing – review & editing
Camila Hamond: Role: InvestigationRole: ResourcesRole: Writing – review & editing
Melissa Macías-Rioseco: Role: InvestigationRole: Methodology
Clara Menéndez: Role: MethodologyRole: Resources
Alberto Mortola: Role: MethodologyRole: Resources
Mathieu Picardeau: Role: Formal analysisRole: ResourcesRole: SupervisionRole: Writing – review & editing
Jair Quintero: Role: Methodology
Cristina Ríos: Role: Methodology
Víctor Rodríguez: Role: Methodology
Agustín Romero: Role: Methodology
Gustavo Varela: Role: InvestigationRole: Supervision
Rodolfo Rivero: Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
SupervisionRole: Writing – review & editing
Felipe Schelotto:
ORCID: http://orcid.org/0000-0003-3379-1032
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: SupervisionRole: Writing – review & editing
Franklin Riet-Correa: Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: ResourcesRole: SupervisionRole: Writing – original draftRole: Writing
– review & editing
Alejandro Buschiazzo:
ORCID: http://orcid.org/0000-0002-2509-6526
Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: Project administrationRole:
SupervisionRole: Writing – original draftRole: Writing – review & editing
Jenifer Coburn: Role: Editor
Journal
Journal ID (nlm-ta): PLoS Negl Trop Dis
Journal ID (iso-abbrev): PLoS Negl Trop Dis
Journal ID (publisher-id): plos
Journal ID (pmc): plosntds
Title:
PLoS Neglected Tropical Diseases
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1935-2727
ISSN
(Electronic):
1935-2735
Publication date
(Electronic):
13
September
2018
Publication date Collection:
September
2018
Volume: 12
Issue: 9
Electronic Location Identifier: e0006694
Affiliations
[1
]
Laboratorio de Microbiología Molecular y Estructural, Institut Pasteur de Montevideo,
Montevideo, Uruguay
[2
]
Unidad Mixta UMPI, Institut Pasteur de Montevideo + Instituto Nacional de Investigación
Agropecuaria INIA, Montevideo, Uruguay
[3
]
Departamento de Bacteriología, División Laboratorios Veterinarios “Miguel C. Rubino”
Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Montevideo, Uruguay
[4
]
Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina,
Universidad de la República, Montevideo, Uruguay
[5
]
División Laboratorios Veterinarios “Miguel C. Rubino” Laboratorio Regional Noroeste,
Ministerio de Ganadería, Agricultura y Pesca, Paysandú, Uruguay
[6
]
División Laboratorios Veterinarios “Miguel C. Rubino” Laboratorio Regional Este, Ministerio
de Ganadería, Agricultura y Pesca, Treinta y Tres, Uruguay
[7
]
Instituto Nacional de Investigación Agropecuaria INIA, Estación Experimental La Estanzuela,
Colonia, Uruguay
[8
]
Unité de Biologie des Spirochètes, Institut Pasteur, Paris, France
[9
]
Joint International Unit « Integrative Microbiology of Zoonotic Agents » IMiZA, Institut
Pasteur de Montevideo, Montevideo, Uruguay / Institut Pasteur, Paris, France
[10
]
Département de Microbiologie, Institut Pasteur, Paris, France
Medical College of Wisconsin, UNITED STATES
Author notes
I have read the journal's policy and the authors of this manuscript have the following
competing interests: Alejandro Buschiazzo is an Associate Editor of PLoS Neglected
Tropical Diseases. Mathieu Picardeau is a Deputy Editor of PLoS Neglected Tropical
Diseases.
‡ These authors also contributed equally to this work
¶ Membership of the Grupo de Trabajo Interinstitucional de Leptospirosis Consortium
is provided in
S1 Text.
Author information
Article
Publisher ID:
PNTD-D-18-00206
DOI: 10.1371/journal.pntd.0006694
PMC ID: 6136691
PubMed ID: 30212451
SO-VID: 3c5fed78-4642-479f-a137-fecd64e57ddc
Copyright © © 2018 Zarantonelli et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 8
February
2018
Date
accepted
: 16
July
2018
Page count
Figures: 2,
Tables: 2,
Pages: 22
Funding
Funded by: Agencia Nacional de Investigación e Innovación (UY)
Award ID: ALI_1_2014_1_4982
Award Recipient
:
ORCID: http://orcid.org/0000-0002-2509-6526
Alejandro Buschiazzo
Funded by: Agencia Nacional de Investigación e Innovación (UY)
Award ID: FSA_1_2013_1_12557
Award Recipient
:
ORCID: http://orcid.org/0000-0002-2509-6526
Alejandro Buschiazzo
Funded by: Ministry of Industry, Industrial Funds program of the National Direction of Industries,
Uruguay
Award ID: 2016-8-2-002671
Funded by: Agencia Nacional de Investigación e Innovación (UY)
Award ID: FSA_X_2014_1_105696
Award Recipient
:
Franklin Riet-Correa
Funded by: FOCEM (MERCOSUR Structural Convergence Fund)
Award ID: COF 03/11
This work was supported by grants from the Agencia Nacional de Investigacion e Innovación
(ANII Uruguay) #ALI_1_2014_1_4982 (AB), #FSA_1_2013_1_12557 (AB) and #FSA_X_2014_1_105696
(FR-C). Partial support was also obtained through grants from Institut Pasteur Paris
(PTR Program) #PTR30-17, Ministerio de Industria, Energia y Mineria (MIEM, Industrial
Funds program) #2016-8-2-002671, and FOCEM (MERCOSUR Structural Convergence Fund)
#COF03/11; and through institutional funds from Instituto Nacional de Investigacion
Agropecuaria (INIA), Ministerio de Ganaderia, Agricultura y Pesca (MGAP), Instituto
de Higiene (IH, UdelaR University Medical School) and Institut Pasteur de Montevideo
(IPMontevideo). The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Leptospira
Subject:
Leptospira Interrogans
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Leptospira
Subject:
Leptospira Interrogans
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Leptospira
Subject:
Leptospira Interrogans
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Urine
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Urine
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Urine
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Urine
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Leptospira
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Leptospira
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Leptospira
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Bacterial Diseases
Subject:
Leptospirosis
Subject:
Medicine and Health Sciences
Subject:
Tropical Diseases
Subject:
Neglected Tropical Diseases
Subject:
Leptospirosis
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Zoonoses
Subject:
Leptospirosis
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Medicine and Health Sciences
Subject:
Epidemiology
Subject:
Infectious Disease Epidemiology
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Infectious Disease Epidemiology
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Bovines
Subject:
Cattle
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Ruminants
Subject:
Cattle
Custom metadata
Data Availability All relevant data are within the paper and its Supporting Information files. Sequence
files for secY genes are available from the GenBank database (accession numbers MH325388,
MH325389, MH325390, MH325391, MH325392, MH325393, MH325394, MH325395, MH325396, MH325397,
MH325398, MH325399, MH325400, MH325401, MH325402, MH325403, MH325404, MH325405, MH325406,
MH325407, MH325408, MH325409, MH325410, MH325411, MH325412, MH325413, MH325414, MH325415,
MH325416, MH325417, MH325418, MH325419, MH325420, MH325421, MH325422, MH325423, MH325424,
MH325425, MH325426, MH325427, MH376290, MH376291, MH376292, MH376293). Sequence files
for rrs16S genes are available from the GenBank database (accession numbers MH329307,
MH329308, MH329309, MH329310, MH329311, MH329312, MH329313, MH329314, MH329315, MH329316,
MH329317, MH329318, MH329319, MH329320, MH329321, MH329322, MH329323, MH329324, MH329325,
MH329326, MH329327, MH329328, MH329329, MH329330, MH329331, MH329332, MH329333, MH329334,
MH329335, MH329336, MH329337, MH329338, MH329339, MH329340, MH329341, MH329342, MH329343,
MH329344, MH329345, MH329346, MH374851, MH374852, MH374853, MH374854).