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      A DNA enzyme that cleaves RNA.

      1 ,
      Chemistry & biology
      Elsevier BV
      NASA Discipline Exobiology, Non-NASA Center

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          Abstract

          Several types of RNA enzymes (ribozymes) have been identified in biological systems and generated in the laboratory. Considering the variety of known RNA enzymes and the similarity of DNA and RNA, it is reasonable to imagine that DNA might be able to function as an enzyme as well. No such DNA enzyme has been found in nature, however. We set out to identify a metal-dependent DNA enzyme using in vitro selection methodology.

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          Author and article information

          Journal
          Chem Biol
          Chemistry & biology
          Elsevier BV
          1074-5521
          1074-5521
          Dec 1994
          : 1
          : 4
          Affiliations
          [1 ] Department of Chemistry, Scripps Research Institute, La Jolla, CA 92037, USA.
          Article
          1074-5521(94)90014-0
          10.1016/1074-5521(94)90014-0
          9383394
          3c7d53e6-43ca-4251-b23e-5f06cbef6d72
          History

          NASA Discipline Exobiology,Non-NASA Center
          NASA Discipline Exobiology, Non-NASA Center

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