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      An unusual cause of cerebellar hemorrhage in a young patient: essential thrombocythemia.

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          Abstract

          Essential thrombocythemia (ET) is a risk factor for ischemic stroke and, far more rarely, hemorrhage. We report the case of an untreated 32-year-old woman with a history of JAK2 V617F-positive ET with cerebellar and subarachnoid hemorrhages without evidence of sinus vein thrombosis. She was commenced on oral cytotoxic and antiplatelet therapy. This case report discusses the underlying mechanism of hemorrhagic thrombocythemia and the management dilemma presented by the recommended treatment implications.

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          Author and article information

          Journal
          J Stroke Cerebrovasc Dis
          Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
          Elsevier BV
          1532-8511
          1052-3057
          March 4 2014
          : 23
          : 5
          Affiliations
          [1 ] Department of Neurology, Royal North Shore Hospital, Sydney, Australia; Department of Medicine, University of Sydney, Sydney, Australia. Electronic address: robert.adam@sydney.edu.au.
          [2 ] Department of Neurology, Royal North Shore Hospital, Sydney, Australia.
          [3 ] Department of Radiology, Royal North Shore Hospital, Sydney, Australia.
          [4 ] Department of Medicine, University of Sydney, Sydney, Australia.
          [5 ] Department of Neurology, Royal North Shore Hospital, Sydney, Australia; Department of Medicine, University of Sydney, Sydney, Australia.
          Article
          S1052-3057(13)00528-4
          10.1016/j.jstrokecerebrovasdis.2013.12.013
          24582788
          3d125d0b-3d1c-443d-bb03-2bb127741ba2
          History

          essential thrombocythaemia,Hemorrhagic stroke,acquired von Willebrand disease,antiplatelet,myeloproliferative disorder,young stroke

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