Coronavirus (2019-nCoV) pandemic has placed an overwhelming health and economic burden
 and, most likely, has had a dramatic impact on emotional regulation. An Italian
32-year-old healthy right-handed woman, resident in Piacenza, Italy, one of the red
areas, underwent a functional MRI with a visual task where happy faces and threat-related
cues were shown. Images of an intensive care unit correlated with a stronger activation
of bilateral amygdala than did other tasks (p < 0.05, corrected) (Fig. 1). Indeed,
when rating fear, the amygdala gives priority to 2019-nCoV in people subjected to
the psychological consequences of the pandemic. When emotion takes over, the amygdala
hijack occurs .
Statement of Ethics
Human and animal studies have been approved by the local Ethics Committee and, therefore,
been performed in accordance with the ethical standards laid down in the 1964 Declaration
of Helsinki and its later amendments. Specific national laws have been observed, too.
The patient gave written informed consent for publication of the case, including brain
The authors declare that they have no conflicts of interest concerning this article.
This research received no specific grant from any funding agency in the public, commercial,
or not-for-profit sectors. No financial support was provided for the research, authorship,
and/or publication of this article.
Study concepts: N. Morelli and P. Immovilli. Study design: N. Morelli, M. Spallazzi,
and D. Colombi. Data analysis/interpretation: N. Morelli. Manuscript preparation and
definition of intellectual content: N. Morelli and E. Rota. Manuscript editing: N.
Morelli and E. Rota. Manuscript revision/review: D. Guidetti and E. Michieletti.