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      Whole-body retention and fetal uptake of 65Zn in pregnant mice fed a Zn-deficient diet.

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          Abstract

          Whole-body retention and fetal uptake of 65Zn under a Zn-deficient diet were studied in pregnant mice in the late gestational stage after a single oral administration of 65Zn. Whole-body retentions were much greater in mice given a Zn-deficient diet than in those given a Zn-normal diet. Accordingly, the amount of 65Zn transmitted to the offspring in utero was greater in the Zn-deficient diet group. In another experiment, fetal uptake of 65Zn in dams on gestation day 17 was examined over a period of 24 hr after a single intravenous administration of 65Zn to the Zn-deficient and Zn-normal animals. There was no major difference in fetal uptake between the two groups, indicative that approximately a similar proportion of the 65Zn retained in the maternal body was transmitted to the in utero offspring in both groups.

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          Author and article information

          Journal
          J Radiat Res
          Journal of radiation research
          Japan Radiation Research Society
          0449-3060
          0449-3060
          Sep 1995
          : 36
          : 3
          Affiliations
          [1 ] Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Japan.
          Article
          10.1269/jrr.36.196
          8558496
          3dd094ac-1db1-4717-b8e7-f69b41859dca
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