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      Bio-monitoring of persistent organochlorines in human milk and blood samples from sub-Himalayan region of India.

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          Abstract

          In the present study, concentrations of organochlorine pesticide residues viz. Dichlorodiphenyltrichloroethane and its metabolites (DDTs) and Hexachlorocyclohexane isomers (HCHs) in human breast milk and human blood samples, collected from several high altitude regions of Garhwal Himalaya in Uttarakhand, India viz. Devprayag, Chamoli, Uttarkashi, Joshimath, Bhatwari and Gangnani (altitude ranging from 472 to 1,982 m above sea level) were determined. Mean concentrations of HCH and DDT in human milk samples ranged from 4.53 to 34.32 mg/kg and 6.09 to 12.98 mg/kg, respectively. While the human blood showed mean values ranging from 6.64 to 281.7 μg/L and 12.37 to 104.10 μg/L for HCH and DDT, respectively. The study showed much higher concentrations of organochlorine residue contamination in the Garhwal region as compared to other parts of India. Risk assessments for infants were also calculated and were found within WHO limits.

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          Author and article information

          Journal
          Bull Environ Contam Toxicol
          Bulletin of environmental contamination and toxicology
          Springer Science and Business Media LLC
          1432-0800
          0007-4861
          Sep 2012
          : 89
          : 3
          Affiliations
          [1 ] National Institute of Malaria Research, Field Station, Sec-3, Health Centre, BHEL, Haridwar, India. ssrai31@gmail.com
          Article
          10.1007/s00128-012-0741-5
          22885541
          3ddf35c5-b322-4e23-96cc-9fe64d5ba3b5

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