Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
2
February
2017
Publication date Collection: 2017
Volume: 12
Issue: 2
Electronic Location Identifier: e0170843
Affiliations
[1
]Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United
States of America
[2
]Department of Pediatrics, Division of Genetics and Genomic Medicine, University of
California Irvine, Irvine, California, United States of America
Tel Aviv University, ISRAEL
Author notes
Competing Interests: All authors were full time paid employees of Ambry Genetics at the time the study
was conducted. This does not alter our adherence to PLOS ONE policies on sharing data
and materials.
-
-
Formal analysis: HL H-ML JC HV.
-
-
Methodology: HL KDF LS ST SB ECC.
-
-
Writing – original draft: HL KDF LS ST ECC.
-
Writing – review & editing: HL KDF HV H-ML WM LS ST JC SB ECC.
Article
Publisher ID:
PONE-D-16-35058
DOI: 10.1371/journal.pone.0170843
PMC ID: 5289469
PubMed ID: 28152038
SO-VID: 3dea02b5-95ec-45be-b9e4-d9287dd13597
Copyright © © 2017 LaDuca et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Ambry Genetics provided support in the form of salaries for all authors, but did not
have any additional role in the study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
DNA sequencing
Subject:
Next-Generation Sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
DNA sequencing
Subject:
Next-Generation Sequencing
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Transcriptome Analysis
Subject:
Next-Generation Sequencing
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Transcriptome Analysis
Subject:
Next-Generation Sequencing
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Complexity
Subject:
Introns
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Complexity
Subject:
Introns
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Polymer Chemistry
Subject:
Macromolecules
Subject:
Polymers
Subject:
Physical Sciences
Subject:
Materials Science
Subject:
Materials by Structure
Subject:
Polymers
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Sequencing Techniques
Subject:
Nucleotide Sequencing
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Sequencing Techniques
Subject:
Nucleotide Sequencing
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
DNA sequencing
Subject:
Gene Sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
DNA sequencing
Subject:
Gene Sequencing
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Alignment
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine