Biodistribution and radiation dosimetry for the chemokine receptor CXCR4-targeting probe 68Ga-pentixafor.

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Abstract

(68)Ga-pentixafor is a promising PET tracer for imaging the expression of the human chemokine receptor 4 (CXCR4) in vivo. The whole-body distribution and radiation dosimetry of (68)Ga-pentixafor were evaluated.

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Journal

Journal ID (iso-abbrev): J. Nucl. Med.

Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

ISSN (Electronic): 1535-5667

ISSN (Print): 0161-5505

Publication date (Electronic): Mar 2015

Volume: 56

Issue: 3

Affiliations

[1 ] Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California Herrmann_K1@ukw.de.

[2 ] Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

[3 ] Pharmaceutical Radiochemistry, Technische Universität München, Munich, Germany Scintomics GmbH, Fürstenfeldbruck, Germany.

[4 ] Pharmaceutical Radiochemistry, Technische Universität München, Munich, Germany.

[5 ] Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California.

[6 ] III. Medical Department of Hematology and Medical Oncology, Technische Universität München, Munich, Germany; and.

[7 ] Division of Hematology and Medical Oncology, Department of Internal Medicine II, Universitätsklinikum Würzburg, Würzburg, Germany.

[8 ] Scintomics GmbH, Fürstenfeldbruck, Germany.

Article

Publisher Item ID: jnumed.114.151647

DOI: 10.2967/jnumed.114.151647

PubMed ID: 25698782

SO-VID: 3e0ed3e0-b79f-44ec-9ce8-e84b4cf390d3

History

Keywords: 68Ga,CXCR4,PET,dosimetry

Data availability:

Keywords: 68Ga, CXCR4, PET, dosimetry

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