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      Case report: Management of septic knee arthritis with Pseudomonas aeruginosa by arthroscopic debridement and lavage with diluted povidone iodine

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          Abstract

          Introduction

          Septic knee arthritis after elective arthroscopic procedures is a rare surgical emergency, with Pseudomonas aeruginosa even more rarely causing the infection. The treatment by arthroscopic debridement and lavage with diluted Povidone-Iodine has potential benefits that may be useful in improving the prognosis for patients. This case report discusses the potential benefits of using antiseptics like Povidone-Iodine in the washout of the affected joint.

          Presentation of case

          We present a patient with post arthroscopic septic knee arthritis caused by P. aeruginosa treated successfully by arthroscopic synovectomy and washout with normal saline and diluted povidone‑iodine, and prolonged antimicrobial therapy.

          Discussion

          Preceding reports of P. aeruginosa suggest intraoperative factors, postoperative factors, and host factors that may lead to this uncommon infection. There is controversy over the optimal management regarding arthroscopic versus open debridement, and the choice of the irrigating fluid.

          Conclusion

          The use of antiseptics like Povidone-Iodine in the washout procedure may lead to improved outcomes if used for a short controlled period of time and followed by copious irrigation with saline. Further studies must be done to determine the efficacy and risk-to-benefit ratio of this method.

          Highlights

          • Pseudomonas aeruginosa causing septic arthritis without any risk factors are unusual.

          • Treatment approach for septic knee arthritis is controversial.

          • The type of irrigating fluid used in septic arthritis washout is not well defined by international guidelines

          • Use of 2.5% Povidine-Iodine in joint lavage for a short time is safe and effective in treating septic arthritis.

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          Most cited references16

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          The PROCESS 2020 Guideline: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) Guidelines

          The PROCESS Guidelines were first published in 2016 and were last updated in 2018. They provide a structure for reporting surgical case series in order to increase reporting robustness and transparency, and are used and endorsed by authors, journal editors and reviewers alike. In order to drive forwards reporting quality, they must be kept up to date. As such, we have updated these guidelines via a DELPHI consensus exercise.
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            Acute septic arthritis.

            Acute septic arthritis may develop as a result of hematogenous seeding, direct introduction, or extension from a contiguous focus of infection. The pathogenesis of acute septic arthritis is multifactorial and depends on the interaction of the host immune response and the adherence factors, toxins, and immunoavoidance strategies of the invading pathogen. Neisseria gonorrhoeae and Staphylococcus aureus are used in discussing the host-pathogen interaction in the pathogenesis of acute septic arthritis. While diagnosis rests on isolation of the bacterial species from synovial fluid samples, patient history, clinical presentation, laboratory findings, and imaging studies are also important. Acute nongonococcal septic arthritis is a medical emergency that can lead to significant morbidity and mortality. Therefore, prompt recognition, rapid and aggressive antimicrobial therapy, and surgical treatment are critical to ensuring a good prognosis. Even with prompt diagnosis and treatment, high mortality and morbidity rates still occur. In contrast, gonococcal arthritis is often successfully treated with antimicrobial therapy alone and demonstrates a very low rate of complications and an excellent prognosis for full return of normal joint function. In the case of prosthetic joint infections, the hardware must be eventually removed by a two-stage revision in order to cure the infection.
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              Antiseptics in the era of bacterial resistance: a focus on povidone iodine

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                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                03 August 2021
                August 2021
                03 August 2021
                : 85
                : 106262
                Affiliations
                [a ]Faculty of Medicine, Department of General Surgery and Special Surgery, Yarmouk University, Jordan
                [b ]Faculty of Medicine, Yarmouk University, Jordan
                [c ]Irbid Health Directorate, Ministry of Health, Jordan
                [d ]University of Jordan Hospital, Jordan
                [e ]Clinical lecturer of Neurosurgery, Department of Special Surgery, Faculty of Medicine, Al-Balqa Applied University, Jordan
                [f ]Faculty of Medicine, Mutah University, Jordan
                Author notes
                [* ]Corresponding author. salah.daradkeh@ 123456yu.edu.jo
                Article
                S2210-2612(21)00764-1 106262
                10.1016/j.ijscr.2021.106262
                8350496
                34388897
                3e144b60-b7f2-47db-80a9-a4106dadc1a5
                © 2021 The Authors

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 6 July 2021
                : 29 July 2021
                : 1 August 2021
                Categories
                Case Report

                ml, milliliters,l, litres,ap view, anteroposterior view,p. aeruginosa, pseudomonas aeruginosa,septic arthritis,pseudomonas aeruginosa,arthroscopy,povidone-iodine,case report

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