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      Torsade de pointes: The long-short initiating sequence and other clinical features: observations in 32 patients

      , , , ,
      Journal of the American College of Cardiology
      Elsevier BV

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          QUINIDINE SYNCOPE. PAROXYSMAL VENTRICULAR FIBRILLATION OCCURRING DURING TREATMENT OF CHRONIC ATRIAL ARRHYTHMIAS.

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            Q-T prolongation and polymorphous ("torsade de pointes") ventricular arrhythmias associated with organophosphorus insecticide poisoning.

            It is not generally appreciated in the Western world that organophosphorus poisoning may be associated with a serious and often fatal cardiac complication: Q-T interval prolongation with malignant ventricular arrhythmias of the "torsade de pointes" type. This insidious complication may lead to delayed, sudden death after the patients appears to be well on the way to recovery from the other, more dramatic respiratory and neurologic symptoms. In this study 15 patients with organophosphorus poisoning are described. Q-T prolongation was observed in 14 and malignant tachyarrhythmias in 6. In view of the dismal prognosis of these patients, ventricular pacing, previously used with success in other conditions associated with this syndrome, was tried in four patients and successfully shortened the Q-T interval and eliminated the arrhythmias. Isoproterenol did the same in a fifth patient. Awareness of this lethal, but preventable complication of organophosphorus poisoning is called for. Careful electrocardiographic monitoring is necessary until the Q-T interval returns to normal. Electrical pacing appears to be the treatment of choice for the tachyarrhythmias.
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              Temporal dispersion of recovery of excitability in atrium and ventricle as a function of heart rate.

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                Author and article information

                Journal
                Journal of the American College of Cardiology
                Journal of the American College of Cardiology
                Elsevier BV
                07351097
                November 1983
                November 1983
                : 2
                : 5
                : 806-817
                Article
                10.1016/S0735-1097(83)80226-5
                3e3cd6b4-e865-4bfc-9ea4-592ccb1226dd
                © 1983

                http://www.elsevier.com/tdm/userlicense/1.0/

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