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      Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis.

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          Abstract

          To update the evidence for the efficacy of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with rheumatoid arthritis (RA) to inform European League Against Rheumatism (EULAR) Task Force treatment recommendations.

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          Author and article information

          Journal
          Ann. Rheum. Dis.
          Annals of the rheumatic diseases
          BMJ
          1468-2060
          0003-4967
          Jun 2017
          : 76
          : 6
          Affiliations
          [1 ] Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
          [2 ] NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
          [3 ] Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan.
          [4 ] .
          [5 ] Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stokholm, Sweden.
          [6 ] Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.
          [7 ] Department of Medicine, Hietzing Hospital, Vienna, Austria.
          [8 ] Department of Rheumatology, University Medical Center Utrecht, Utrecht, The Netherlands.
          [9 ] Department of Rheumatology, Charité University Medicine Berlin, Berlin, Germany.
          [10 ] Department of Rheumatology, Paris Descartes University, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, INSERM (U1153): Clinical Epidemiology and Biostatistics, Paris, France.
          [11 ] Department of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.
          [12 ] EULAR Standing Committee of People with Arthritis/Rheumatism in Europe.
          [13 ] Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology Center, Amsterdam, The Netherlands.
          [14 ] Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, The Netherlands.
          [15 ] Department of Rheumatology, Zuyderland Medical Center, Heerlen, The Netherlands.
          Article
          annrheumdis-2016-210713
          10.1136/annrheumdis-2016-210713
          28283512
          3e8c961a-a876-4a02-bfcc-891ca8e8d562
          History

          Anti-TNF,DMARDs (biologic),Rheumatoid Arthritis
          Anti-TNF, DMARDs (biologic), Rheumatoid Arthritis

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