Dopaminergic imaging separates normal pressure hydrocephalus from its mimics.

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Abstract

Idiopathic normal pressure hydrocephalus (iNPH) and iNPH mimics (i.e., Parkinson's disease, progressive supranuclear palsy or dementia with Lewy bodies) share similar clinical features, and discrimination between both conditions relies on invasive time-consuming investigations. This study aims to compare [123I]FP-CIT SPECT imaging-visual rating and semiquantitative values-between iNPH and iNPH mimics.

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Journal

Journal ID (iso-abbrev): J Neurol

Title: Journal of neurology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-1459

ISSN (Print): 0340-5354

Publication date (Electronic): Oct 2018

Volume: 265

Issue: 10

Affiliations

[1 ] Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland. gilles.allali@hcuge.ch.

[2 ] Division of Cognitive and Motor Aging, Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, Newyork, USA. gilles.allali@hcuge.ch.

[3 ] Department of Neurology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland. gilles.allali@hcuge.ch.

[4 ] Division of Nuclear Medicine, and Molecular Imaging, Department of Medical Imaging and Information Sciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

[5 ] Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

[6 ] Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Article

Publisher Item ID: 10.1007/s00415-018-9029-y

DOI: 10.1007/s00415-018-9029-y

PubMed ID: 30155736

SO-VID: 3ea6dcc9-30b3-4b06-a3bb-67b00f15a09b

Keywords: Normal pressure hydrocephalus,Mimics,Aging,[123I]FP-CIT SPECT imaging,Parkinsonism

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Keywords: Normal pressure hydrocephalus, Mimics, Aging, [123I]FP-CIT SPECT imaging, Parkinsonism

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