Bibliometric Analysis of Functional Magnetic Resonance Imaging Studies on Manual Therapy Analgesia from 2002–2022

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Abstract

Background

Research on the brain mechanisms underlying manual therapy (MT)-induced analgesia has been conducted worldwide. However, no bibliometric analysis has been performed on functional magnetic resonance imaging (fMRI) studies of MT analgesia. To provide a theoretical foundation for the practical application of MT analgesia, this study examined the current incarnation, hotspots, and frontiers of fMRI-based MT analgesia research over the previous 20 years.

Methods

All publications were obtained from the Science Citation Index-Expanded (SCI-E) of Web of Science Core Collection (WOSCC). We used CiteSpace 6.1.R3 to analyze publications, authors, cited authors, countries, institutions, cited journals, references, and keywords. We also evaluated keyword co-occurrences and timelines, and citation bursts. The search was conducted from 2002–2022 and was completed within one day on October 7, 2022.

Results

In total, 261 articles were retrieved. The total number of annual publications showed a fluctuating but overall increasing trend. Author B. Humphreys had the highest number of publications (eight articles) and J. E. Bialosky had the highest centrality (0.45). The United States of America (USA) was the country with the most publications (84 articles), accounting for 32.18% of all publications. Output institutions were mainly the University of Zurich, University of Switzerland, and the National University of Health Sciences of the USA. The Spine (118) and the Journal of Manipulative and Physiological Therapeutics (80) were most frequently cited. The four hot topics in fMRI studies on MT analgesia were “low back pain”, “magnetic resonance imaging”, “spinal manipulation”, and “manual therapy.” The frontier topics were “clinical impacts of pain disorders” and “cutting-edge technical capabilities offered by magnetic resonance imaging”.

Conclusion

fMRI studies of MT analgesia have potential applications. fMRI studies of MT analgesia have linked several brain areas, with the default mode network (DMN) garnering the most attention. Future research should include international collaboration and RCTs on this topic.

Related collections

Most cited references 56

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All references

Author and article information

Journal

Journal ID (nlm-ta): J Pain Res

Journal ID (iso-abbrev): J Pain Res

Journal ID (publisher-id): jpr

Title: Journal of Pain Research

Publisher: Dove

ISSN (Electronic): 1178-7090

Publication date (Electronic): 19 June 2023

Publication date Collection: 2023

Volume: 16

Pages: 2115-2129

Affiliations

[1 ]The Third Clinical Medical College of Zhejiang Chinese Medical University , Hangzhou, Zhejiang, People’s Republic of China

Author notes

Correspondence: Zhi-Zhen Lv; Li-Jiang Lv, The Third Clinical Medical College of Zhejiang Chinese Medical University , No. 548, Binwen Road, Hangzhou, 310053, People’s Republic of China, Tel +86 13750821128; +86 13958107858, Email lvzhizhen1992@163.com; lvlijiang0288@163.com

[*]

These authors contributed equally to this work

Author information

Xing-Chen Zhou http://orcid.org/0000-0002-5700-2942

Yu-Bo Huang http://orcid.org/0000-0002-8748-9763

Shuang-Wei Hong http://orcid.org/0000-0001-6037-7174

Article

Publisher ID: 412658

DOI: 10.2147/JPR.S412658

PMC ID: 10289250

PubMed ID: 37361428

SO-VID: 3eb133e7-02d5-4f0c-bb66-062ed105285f

License:

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

History

Date received : 05 April 2023

Date accepted : 13 June 2023

Page count

Figures: 10, Tables: 7, References: 56, Pages: 15

Funding

Funded by: General Program of National Natural Science Foundation of China;

Funded by: “Pioneer” and “Leading Goose” R&D Program of Zhejiang;

Funded by: Traditional Chinese Medicine Science and Technology Program of Zhejiang;

This study was supported by the General Program of National Natural Science Foundation of China (Grant No. 82274672), the “Pioneer” and “Leading Goose” R&D Program of Zhejiang (Grant No. 2022C03123), the Traditional Chinese Medicine Science and Technology Program of Zhejiang (Grant No. 2020ZX010).