The impact of oral anticoagulation on time to surgery in patients hospitalized with hip fracture.

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Abstract

Current clinical guidelines recommend expedited repair of hip fracture to reduce morbidity and mortality. A significant number of hip fracture patients have concomitant cardiovascular disease requiring anticoagulation. Vitamin K antagonists (VKAs), which have been traditionally used, might be associated with an increased time to surgery (TTS) and it remains unknown what effect direct oral anticoagulants (DOACs) have on this metric. Our objective is to determine how anticoagulation with a VKA or DOAC affects TTS.

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Author and article information

Journal

Journal ID (iso-abbrev): Thromb. Res.

Title: Thrombosis research

Publisher: Elsevier BV

ISSN (Electronic): 1879-2472

ISSN (Print): 0049-3848

Publication date (Electronic): Nov 2015

Volume: 136

Issue: 5

Affiliations

[1 ] Department of Medicine, University of Ottawa at The Ottawa Hospital, 501 Smyth Road, Box 201A, Ottawa, Ontario K1H 8L6, Canada. Electronic address: ttran@toh.on.ca.

[2 ] Département de Médecine Interne, Brest University Hospital, EA3878, bd Tanguy Prigent, 29609 Brest Cedex Brest, France. Electronic address: aurelien.delluc@chu-brest.fr.

[3 ] The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa, Ontario K1Y 4E9, Canada. Electronic address: cdewit@toh.on.ca.

[4 ] The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa, Ontario K1Y 4E9, Canada. Electronic address: wpetrcich@ohri.ca.

[5 ] Department of Medicine, University of Ottawa at The Ottawa Hospital, 501 Smyth Road, Box 201A, Ottawa, Ontario K1H 8L6, Canada; Département de Médecine Interne, Brest University Hospital, EA3878, bd Tanguy Prigent, 29609 Brest Cedex Brest, France; The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa, Ontario K1Y 4E9, Canada. Electronic address: glegal@toh.on.ca.

[6 ] Department of Medicine, University of Ottawa at The Ottawa Hospital, 501 Smyth Road, Box 201A, Ottawa, Ontario K1H 8L6, Canada; The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa, Ontario K1Y 4E9, Canada. Electronic address: mcarrier@toh.on.ca.

Article

Publisher Item ID: S0049-3848(15)30128-6

DOI: 10.1016/j.thromres.2015.09.017

PubMed ID: 26428416

SO-VID: 3ec1e5bc-5d86-4097-994d-d1c974d071c8

History

Keywords: Anticoagulants,Arthroplasty,Hip fractures,Surgery,Warfarin

Data availability:

Keywords: Anticoagulants, Arthroplasty, Hip fractures, Surgery, Warfarin

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