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      A Defense of The-Risks-of-Daily-Life

      research-article
      Kennedy Institute of Ethics Journal
      Johns Hopkins University Press

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          ABSTRACT

          Research examining the safe and effective treatment of diseases and disorders affecting children offers one of the best prospects for improving the medical treatment of children. But the inclusion of children in research raises difficult ethical questions, among them: To how much risk is it permissible to expose children in research? Various thresholds have been proposed to constrain research risks that do not offer children the prospect of direct medical benefit. These proposals include limiting research risks to (1) the risks of routine medical examinations, (2) the risks of participation in charitable activities, (3) the risks of family life, and (4) the risks-of-daily-life. I examine which, if any, of these proposals is defensible. I argue that only the risks-of-daily-life threshold is defensible and I offer a new justification for this risk threshold. I argue that the risks of daily life are justifiable because they are part of a reasonable trade-off between personal safety and our ability to pursue meaningful lives.

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          Most cited references38

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          The framing of decisions and the psychology of choice.

          The psychological principles that govern the perception of decision problems and the evaluation of probabilities and outcomes produce predictable shifts of preference when the same problem is framed in different ways. Reversals of preference are demonstrated in choices regarding monetary outcomes, both hypothetical and real, and in questions pertaining to the loss of human lives. The effects of frames on preferences are compared to the effects of perspectives on perceptual appearance. The dependence of preferences on the formulation of decision problems is a significant concern for the theory of rational choice.
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            When are research risks reasonable in relation to anticipated benefits?

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              American Psychiatric Association

              (2013)
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                Author and article information

                Journal
                Kennedy Inst Ethics J
                Kennedy Inst Ethics J
                Kennedy Institute of Ethics Journal
                Johns Hopkins University Press
                1054-6863
                1086-3249
                September 2017
                : 27
                : 3
                : 413-442 (pp. 413-442)
                Article
                ken_672172
                10.1353/ken.2017.0033
                5691379
                28989167
                3ec723f3-0ff7-4610-b8e2-367714d1bbee
                Copyright © 2017 Johns Hopkins University Press

                This article is distributed under the terms of the Creative Commons Attribution 4.0 International License

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