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      An 11-Year Analysis of Emergency Presentations of Melioidosis in Northeastern Malaysia.

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          Abstract

          A neglected tropical disease, melioidosis is known to have variability in clinical presentations. Here, we described clinical features that should alert the physicians on the possibility of melioidosis. In this review of 86 cases from 2001 to 2011, the common presentations of melioidosis in the Emergency Department (ED), Hospital Universiti Sains Malaysia were; male gender (79.1 %), in working age group (47.8 ± 15.2 year-old), worked in contact with soil (73.3 %), presented with fever (91.9 %), in rainy season (55.8 %), have underlying diabetes mellitus (79.1 %), have leukocytosis (67.4 %) and high blood glucose (62.8 %) during presentation. In 34.9 % of cases, the antimicrobials were initiated at the ED and only 10.5 % include antimelioid drugs. Thirty-one patients (36.0 %) died due to melioidosis and 51.6 % of this were within 48 h of admission. Despite high mortality rate, the clinical awareness on the possibility of melioidosis among emergency physicians is still low and need to be strengthened.

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          Author and article information

          Journal
          J Immigr Minor Health
          Journal of immigrant and minority health
          Springer Nature
          1557-1920
          1557-1912
          Jun 2017
          : 19
          : 3
          Affiliations
          [1 ] Department of Emergency Medicine, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia.
          [2 ] Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia.
          [3 ] Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia. zakuan@usm.my.
          Article
          10.1007/s10903-016-0429-8
          10.1007/s10903-016-0429-8
          27160769
          3ed0029b-2e07-4667-b22c-3312e2b52ac2
          History

          Emergency presentations,Malaysia,Melioidosis,Neglected tropical diseases

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