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The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

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      Abstract

      The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13354/full. G protein‐coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and GRAC and provides a permanent, citable, point‐in‐time record that will survive database updates.

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      Affiliations
      [ 1 ] School of Biomedical SciencesUniversity of Nottingham Medical School Nottingham NG7 2UHUK
      [ 2 ]PIQUR Therapeutics Basel 4057Switzerland
      [ 3 ] School of Physiology and PharmacologyUniversity of Bristol Bristol BS8 1TDUK
      [ 4 ] Neuroscience Division, Medical Education Institute, Ninewells Hospital and Medical School University of Dundee Dundee DD1 9SYUK
      [ 5 ] Centre for Integrative PhysiologyUniversity of Edinburgh Edinburgh EH8 9XDUK
      Journal
      Br J Pharmacol
      Br. J. Pharmacol
      10.1111/(ISSN)1476-5381
      BPH
      British Journal of Pharmacology
      John Wiley and Sons Inc. (Hoboken )
      0007-1188
      1476-5381
      09 December 2015
      December 2015
      : 172
      : 24 , The Concise Guide to PHARMACOLOGY 2015/16. This issue was published by Wiley with financial contributions from the British Pharmacological Society, the International Union of Basic and Clinical Pharmacology, the Wellcome Trust (099156/Z/12/Z]), which supports the website and the University of Edinburgh, who host the guidetopharmacology.org website. ( doiID: 10.1111/bph.v172.24 )
      : 6024-6109
      26650445
      4718211
      10.1111/bph.13354
      BPH13354 10.1111/bph.13354
      © 2015 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.

      This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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      Pages: 86
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      The Concise Guide to PHARMACOLOGY 2015/16
      The Concise Guide to PHARMACOLOGY 2015/16
      Custom metadata
      2.0
      bph13354
      bph13354-hdr-0001
      December 2015
      Converter:WILEY_ML3GV2_TO_NLMPMC version:4.7.5 mode:remove_FC converted:19.01.2016

      Pharmacology & Pharmaceutical medicine

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