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      [Incidental intraplacental gestational choriocarcinoma on a full-term placenta].

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          Abstract

          Of all the gestational trophoblastic tumors, the gestational choriocarcinomas have the worst prognosis and the most uncommon. We report a case diagnosed on a full-term placenta, discovered incidentally. The patient, gravida 2, para 1, delivered a hypotrophic infant at 38 weeks gestation. The placenta was examined in the laboratory to perform anatomo-pathological examination in order to explain the growth retardation. This study revealed the presence of an intraplacental choriocarcinoma. Disease staging was negative for both mother and child, and beta-HCG levels remained at zero. These two factors are rather good prognosis for choriocarcinoma. With this observation, we highlight the added-value of placental examination, which seems essential for any fetal pathology, pathological pregnancy and intrapartum complications. Anatomo-pathological examination must be meticulous and systematized in order to not overlook an intraplacental tumor.

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          Author and article information

          Journal
          Ann Pathol
          Annales de pathologie
          Elsevier BV
          0242-6498
          0242-6498
          Apr 2014
          : 34
          : 2
          Affiliations
          [1 ] Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France. Electronic address: fanny.sauvestre@gmail.com.
          [2 ] Unité de pathologie fœtoplacentaire, université Bordeaux-Segalen, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
          [3 ] Service d'anatomie et cytologie pathologiques, hôpital Robert-Boulin, 112, rue de la Marne, 33505 Libourne cedex, France.
          [4 ] Service de gynécologie, hôpital Robert-Boulin, 112, rue de la Marne, 33505 Libourne cedex, France.
          [5 ] Service d'anatomie et cytologie pathologiques, CHU Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
          Article
          S0242-6498(14)00039-X
          10.1016/j.annpat.2014.02.009
          24703021
          3f018fdd-6604-4a9b-bfbd-2f091c00fb34
          History

          Placenta,Tumeur trophoblastique,Trophoblastic tumor,Choriocarcinome intra-placentaire gestationnel,Choriocarcinome in situ,In situ choriocarcinoma,Intraplacental gestational choriocarcinoma

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