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      Oral lichen planus: a clinical and morphometric study of oral lesions in relation to clinical presentation

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          Abstract

          Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical presentations that can be classified as reticular or atrophic-erosive. Sixty-two OLP patients were studied to evaluate the clinical-pathologic characteristics of their OLP lesions and to investigate possible differences in their biological behavior. The most common clinical presentation was the reticular type (62.9% vs 37.1%). Atrophic-erosive presentations showed significantly longer evolution (chi square=4.454; p=0.049), more extensive lesions (chi square=16.211; p=0.000) and more sites affected than reticular ones (chi square=10.048; p=0.002). Atrophic-erosive OLP was more frequently found on the tongue, gingiva and floor of the mouth. No statistically significant differences could be identified between reticular and atrophic-erosive clinical presentations in terms of age, sex, tobacco habit, plasma cortisol level and depth of inflammatory infiltrate. We concluded that the classification of OLP lesions as reticular vs atrophic-erosive is a simple, easy to use classification that can identify clinical presentations with different biological behavior.

          Translated abstract

          O liquen plano oral (LPO) é uma doença inflamatória crónica com diferentes apresentações clínicas que podem ser classificadas como reticuladas ou atrófico-erosivas. Sessenta e dois pacientes com LPO foram estudados para avalidar as características clínicas/patológicas das suas lesões de LPO e investigar possíveis diferenças no seu comportamento biológico. A forma clínica mais comum foi a de tipo reticular (62,9% vs 37,1%). As formas atrófico-erosivas apresentaram um tempo de evolução significativamente maior (chi quadrado=4,454; p=0,049), lesões mais extensas (chi quadrado=16,211; p=0,000) e afetaram a mais localizações em comparação com as lesões reticulares (chi quadrado=10,048; p= 0,002). A forma atrófico-erosiva de LPO foi encontrada mais frequentemente na língua, gengiva e pavimento da boca. Não foram encontradas diferenças significativas entre as formas reticular e atrófico-erosivas em termos de idade, sexo, hábito tabágico, niveis plasmáticos de cortisol e profundidade de infiltrado inflamatório. Concluímos que a classificaçao de lesões de LPO como reticular vs atrófico-erosivo é uma classificaçao simples e facil de usar, que pode identificar apresentações clínicas com diferentes comportamentos biológicos.

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          Most cited references 18

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          Oral lichen planus: 1. A clinical evaluation of 115 cases

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            Oral lichen planus and diabetes mellitus: A clinico-pathological study

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              Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response

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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                bdj
                Brazilian Dental Journal
                Braz. Dent. J.
                Fundação Odontológica de Ribeirão Preto (Ribeirão Preto )
                1806-4760
                2004
                : 15
                : 1
                : 9-12
                Affiliations
                [1 ] Universidad de Santiago de Compostela Spain
                Article
                S0103-64402004000100002
                10.1590/S0103-64402004000100002
                Product
                Product Information: website
                Categories
                DENTISTRY, ORAL SURGERY & MEDICINE

                Dentistry

                oral lichen planus, clinical classification, morphometry

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