17
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Acute lung injury in leptospirosis: clinical and laboratory features, outcome, and factors associated with mortality.

      Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
      Acute Disease, Adolescent, Adult, Cohort Studies, Creatinine, blood, Female, Follow-Up Studies, Hemorrhage, etiology, mortality, therapy, Humans, Leptospira, isolation & purification, Leptospirosis, complications, microbiology, Lung, pathology, Lung Diseases, Male, Middle Aged, Multivariate Analysis, Potassium, Prospective Studies, Respiration, Artificial, Survival Analysis, Survival Rate

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Forty-two consecutive patients with leptospirosis and acute lung injury who were mechanically ventilated were analyzed in a prospective cohort study. Nineteen patients (45%) survived, and 23 (55%) died. Multivariate analysis revealed that 3 variables were independently associated with mortality: hemodynamic disturbance (odds ratio [OR], 6.0; 95% confidence interval [CI], 0.9-38.8; P=. 047), serum creatinine level >265.2 micromol/L (OR, 10.6; 95% CI, 0. 9-123.7; P =.026), and serum potassium level >4.0 mmol/L (OR, 19.9; 95% CI, 1.2-342.8; P=.009). These observations can be used to identify factors associated with mortality early in the course of severe respiratory failure in leptospirosis.

          Related collections

          Author and article information

          Comments

          Comment on this article