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      Practical implementation of artificial intelligence algorithms in pulmonary auscultation examination

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          Abstract

          Lung auscultation is an important part of a physical examination. However, its biggest drawback is its subjectivity. The results depend on the experience and ability of the doctor to perceive and distinguish pathologies in sounds heard via a stethoscope. This paper investigates a new method of automatic sound analysis based on neural networks (NNs), which has been implemented in a system that uses an electronic stethoscope for capturing respiratory sounds. It allows the detection of auscultatory sounds in four classes: wheezes, rhonchi, and fine and coarse crackles. In the blind test, a group of 522 auscultatory sounds from 50 pediatric patients were presented, and the results provided by a group of doctors and an artificial intelligence (AI) algorithm developed by the authors were compared. The gathered data show that machine learning (ML)–based analysis is more efficient in detecting all four types of phenomena, which is reflected in high values of recall (also called as sensitivity) and F1-score.

          Conclusions: The obtained results suggest that the implementation of automatic sound analysis based on NNs can significantly improve the efficiency of this form of examination, leading to a minimization of the number of errors made in the interpretation of auscultation sounds.

          What is Known:

          Auscultation performance of average physician is very low. AI solutions presented in scientific literature are based on small data bases with isolated pathological sounds (which are far from real recordings) and mainly on leave-one-out validation method thus they are not reliable.
          What is New:

          AI learning process was based on thousands of signals from real patients and a reliable description of recordings was based on multiple validation by physicians and acoustician resulting in practical and statistical prove of AI high performance.

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          Most cited references9

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          Convolutional Recurrent Neural Networks for Polyphonic Sound Event Detection

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            Towards the standardisation of lung sound nomenclature

            Auscultation of the lung remains an essential part of physical examination even though its limitations, particularly with regard to communicating subjective findings, are well recognised. The European Respiratory Society (ERS) Task Force on Respiratory Sounds was established to build a reference collection of audiovisual recordings of lung sounds that should aid in the standardisation of nomenclature. Five centres contributed recordings from paediatric and adult subjects. Based on pre-defined quality criteria, 20 of these recordings were selected to form the initial reference collection. All recordings were assessed by six observers and their agreement on classification, using currently recommended nomenclature, was noted for each case. Acoustical analysis was added as supplementary information. The audiovisual recordings and related data can be accessed online in the ERS e-learning resources. The Task Force also investigated the current nomenclature to describe lung sounds in 29 languages in 33 European countries. Recommendations for terminology in this report take into account the results from this survey.
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              Analysis of Respiratory Sounds: State of the Art

              Objective: This paper describes state of the art, scientific publications and ongoing research related to the methods of analysis of respiratory sounds. Methods and material: Review of the current medical and technological literature using Pubmed and personal experience. Results: The study includes a description of the various techniques that are being used to collect auscultation sounds, a physical description of known pathologic sounds for which automatic detection tools were developed. Modern tools are based on artificial intelligence and on technics such as artificial neural networks, fuzzy systems, and genetic algorithms… Conclusion: The next step will consist in finding new markers so as to increase the efficiency of decision aid algorithms and tools.
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                Author and article information

                Contributors
                +48618295124 , h.hafke@amu.edu.pl , hafke@stethome.com
                Journal
                Eur J Pediatr
                Eur. J. Pediatr
                European Journal of Pediatrics
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                0340-6199
                1432-1076
                29 March 2019
                29 March 2019
                2019
                : 178
                : 6
                : 883-890
                Affiliations
                [1 ]StethoMe, Winogrady 18A, 61-663 Poznań, Poland
                [2 ]ISNI 0000 0001 2205 0971, GRID grid.22254.33, Department of Pediatric Pneumonology, Allergology and Clinical Immunology, K. Jonscher Clinical Hospital, , Poznań University of Medical Sciences, ; Szpitalna 27/33, 60-572 Poznań, Poland
                [3 ]ISNI 0000 0001 2097 3545, GRID grid.5633.3, Institute of Acoustics, Faculty of Physics, , Adam Mickiewicz University, Poznań, ; Umultowska 85, 61-614 Poznań, Poland
                Author notes

                Communicated by Peter de Winter

                Article
                3363
                10.1007/s00431-019-03363-2
                6511356
                30927097
                3ff62f79-4861-4c49-a524-66e9a085dc06
                © The Author(s) 2019

                Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 15 January 2019
                : 4 March 2019
                : 6 March 2019
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100005632, Narodowe Centrum Badań i Rozwoju;
                Award ID: POIR.01.01.01-00- 0528/16-00
                Award Recipient :
                Categories
                Original Article
                Custom metadata
                © Springer-Verlag GmbH Germany, part of Springer Nature 2019

                Pediatrics
                auscultation,artificial intelligence,machine learning,respiratory system,stethoscope
                Pediatrics
                auscultation, artificial intelligence, machine learning, respiratory system, stethoscope

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