Blog
About

22
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Angiolymphoid hyperplasia with eosinophilia

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A 45 year old male presented with nodular lesions on the pinna for the past 2 years [Figure 1] Biopsy of the nodule showed prominent epitheloid endothelial cells and increased eosinophils and lymphoplasmacyte infiltrate around blood vessels [Figures 2 and 3] Figure 1 Photograph showing multiple nodular lesions in the ear Figure 2 Histopathology photos showing prominent endothelial cells and increased lymphohistiocytic infiltrates around blood vessels (H and E, ×40) Figure 3 Increased lymphohistiocytic infiltrates and eosinophils around blood vessels (H and E, ×40) Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign disease with distinctive histopathological features.[1] It is characterized by single or multiple skin-colored or plum colored nodules or plaques especially in head and neck region. Kimura's disease, the close differential diagnosis, is characterized by larger lesions, subcutaneous nodules with involvement of salivary glands, and regional lymph nodes.[2] The smaller lesions of ALHE usually require no treatment and undergo spontaneous regression, but larger lesions require therapy. Surgical excision, intralesional corticosteroids, and pulsed dye laser therapy are the mainstay of treatment.

          Related collections

          Most cited references 2

          • Record: found
          • Abstract: found
          • Article: not found

          Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences.

          There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE). We describe the clinical and histopathologic differences between the two diseases. We reviewed clinical findings and histopathologic changes in two cases of Kimura's disease and three cases of ALHE. Kimura's disease shows typical lymphoid follicles. It is associated with lymphadenopathy and is always accompanied by peripheral eosinophilia. ALHE shows typical changes in endothelial cells. It is characterized by superficial papules or nodules with no lymphadenopathy and is less frequently accompanied by peripheral eosinophilia. Kimura's disease and ALHE are separate entities.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Angiolymphoid hyperplasia with eosinophilia (Kimura's disease)

              Bookmark

              Author and article information

              Journal
              Indian Dermatol Online J
              Indian Dermatol Online J
              IDOJ
              Indian Dermatology Online Journal
              Medknow Publications & Media Pvt Ltd (India )
              2229-5178
              2249-5673
              Jan-Apr 2012
              : 3
              : 1
              : 80
              Affiliations
              Department of Dermatology, Amrita Institute of Medical Sciences, Cochin, Kerala, India
              Author notes
              Address for correspondence: Dr. Vinitha Varghese Panicker, Department of Dermatology, Amrita Institute of Medical Sciences, Cochin, Kerala, India. E-mail: vinithavpanicker@ 123456aims.amrita.edu
              IDOJ-3-80
              10.4103/2229-5178.93481
              3481910
              23130278
              Copyright: © Indian Dermatology Online Journal

              This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

              Categories
              Through the Lens

              Dermatology

              Comments

              Comment on this article