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      Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial.

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          Abstract

          In the Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) improved outcome compared with angiography-guided PCI for up to 2 years of follow-up. The aim in this study was to investigate whether the favourable clinical outcome with the FFR-guided PCI in the FAME study persisted over a 5-year follow-up.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          1474-547X
          0140-6736
          Nov 7 2015
          : 386
          : 10006
          Affiliations
          [1 ] Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven, Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
          [2 ] Cardiovascular Center Aalst, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
          [3 ] Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
          [4 ] Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
          [5 ] Medizinische Poliklinik, Campus-Innenstadt, University Hospital, Munich, Germany.
          [6 ] King's College Hospital, London, UK.
          [7 ] Heart Centre, Royal Victoria Hospital, Belfast, UK.
          [8 ] Golden Jubilee National Hospital, Glasgow, UK.
          [9 ] Northeast Cardiology Associates and Eastern Maine Medical Center, Bangor, ME, USA.
          [10 ] Stanford University Medical Center and Palo Alto VA Health Care Systems, Stanford, CA, USA.
          [11 ] Cardiovascular Center Aalst, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium.
          [12 ] Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven, Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands. Electronic address: nico.pijls@inter.nl.net.
          Article
          S0140-6736(15)00057-4
          10.1016/S0140-6736(15)00057-4
          26333474
          4057283f-ffd0-4890-8218-755404bf51bc
          Copyright © 2015 Elsevier Ltd. All rights reserved.
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