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      Plasma N-terminal propeptide of type III procollagen accurately predicts liver fibrosis severity in children with non-alcoholic fatty liver disease.

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          Abstract

          We examined the diagnostic performance of plasma N-terminal propeptide of type III procollagen (PIIINP) levels, aspartate aminotransferase to platelet ratio index (APRI) and Fibrosis-4 (FIB-4) score for predicting non-alcoholic steatohepatitis (NASH) and liver fibrosis stage in children/adolescents with non-alcoholic fatty liver disease (NAFLD).

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          Author and article information

          Journal
          Liver Int
          Liver international : official journal of the International Association for the Study of the Liver
          Wiley
          1478-3231
          1478-3223
          December 2019
          : 39
          : 12
          Affiliations
          [1 ] Hepatology Gastroenterology and Nutrition, Bambino Gesù Children's Hospital, Rome, Italy.
          [2 ] Hepato-Metabolic Disease Unit, IRCCS, Bambino Gesù Children's Hospital, Rome, Italy.
          [3 ] Research Unit of Molecular Genetics of Complex Phenotypes, IRCCS, Bambino Gesù Children's Hospital, Rome, Italy.
          [4 ] Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
          [5 ] Department of Pediatrics, University La Sapienza, Rome, Italy.
          [6 ] Southampton National Institute for Health Research Biomedical Research Centre, Southampton General Hospital, University Hospital Southampton, Southampton, UK.
          [7 ] Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK.
          Article
          10.1111/liv.14225
          31436362
          406a08f5-51ac-40d1-af73-9a2fd178eb1a
          © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
          History

          NAFLD,PIIINP,children,liver fibrosis,procollagen
          NAFLD, PIIINP, children, liver fibrosis, procollagen

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