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      Evaluación positiva de medicamentos: julio y septiembre 2020 Translated title: Positive assessment of drugs: July and October 2020

      brief-report
      , , ,
      Sanidad Militar
      Ministerio de Defensa
      Acalabrutinib (Calquence®), Amikacina (Arikayce Liposomal®), Avapritinib (Ayvakyt®), Belantamab Mafodotin (Blenrep®), Crizanlizumab (Adakveo®), Dapivirina (Dapivirine®), Filgotinib (Jyseleca®), Obiltoxaximab (Obiltoxaximab Sfl®), meningococcal group A, C, W and Y conjugate vaccine (Menquadfi®), Quadrivalent Influenza Vaccine (recombinant, prepared in cell culture) (Supemtek®), Acalabrutinib (Calquence®), Amikacina (Arikayce Liposomal®), Avapritinib (Ayvakyt®), Belantamab Mafodotin (Blenrep®), Crizanlizumab (Adakveo®), Dapivirina (Dapivirine®), Filgotinib (Jyseleca®), Obiltoxaximab (Obiltoxaximab Sfl®), Vacuna Conjugada De Los Grupos Meningocócicos A, C, W E Y (Menquadfi®), Vacuna Contra La Gripe Cuadrivalente Recombinante, Preparada En Cultivo Celular (Supemtek®)

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          Abstract

          RESUMEN Se reseñan los medicamentos evaluados y con dictamen positivo por comisión de expertos de la Agencia Española de Medicamentos y Productos Sanitarios o de la Agencia Europea del Medicamento hechos públicos en julio y septiembre de 2020, y considerados de mayor interés para el profesional sanitario. Se trata de opiniones técnicas positivas que son previas a la autorización y puesta en el mercado del medicamento.

          Translated abstract

          SUMMARY The drugs assessed by the Spanish Agency for Medicines and Health Products or European Medicines Agency made public in July and October 2020, and considered of interest to the healthcare professional, are reviewed. These are positive technical reports prior to the authorization and placing on the market of the product.

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          Most cited references25

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          Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study

          Belantamab mafodotin (GSK2857916), an immunoconjugate targeting B-cell maturation antigen, showed single-agent activity in the phase 1 DREAMM-1 study in heavily pre-treated patients with relapsed or refractory multiple myeloma. We further investigated the safety and activity of belantamab mafodotin in the DREAMM-2 study.
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            Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial

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              Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.

              The up-regulation of P-selectin in endothelial cells and platelets contributes to the cell-cell interactions that are involved in the pathogenesis of vaso-occlusion and sickle cell-related pain crises. The safety and efficacy of crizanlizumab, an antibody against the adhesion molecule P-selectin, were evaluated in patients with sickle cell disease.
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                Author and article information

                Journal
                sm
                Sanidad Militar
                Sanid. Mil.
                Ministerio de Defensa (Madrid, Madrid, Spain )
                1887-8571
                December 2020
                : 76
                : 4
                : 239-244
                Affiliations
                [2] orgnameServicio de Farmacología Clínica
                [1] orgnameServicio de Farmacia Hospitalaria
                [3] Madrid orgnameHospital Central de la Defensa Gómez Ulla orgdiv1Servicio de Farmacología Clínica España
                Article
                S1887-85712020000400239 S1887-8571(20)07600400239
                10.4321/s1887-85712020000400006
                40883a49-c24e-480e-8097-e5c97bac66ae

                http://creativecommons.org/licenses/by/4.0/

                History
                : 03 December 2020
                : 01 December 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 29, Pages: 6
                Product

                SciELO Spain

                Categories
                Nota Técnica

                Obiltoxaximab (Obiltoxaximab Sfl®),Filgotinib (Jyseleca®),Dapivirina (Dapivirine®),Vacuna Conjugada De Los Grupos Meningocócicos A, C, W E Y (Menquadfi®),Vacuna Contra La Gripe Cuadrivalente Recombinante, Preparada En Cultivo Celular (Supemtek®),Acalabrutinib (Calquence®),Amikacina (Arikayce Liposomal®),Avapritinib (Ayvakyt®),Belantamab Mafodotin (Blenrep®),Crizanlizumab (Adakveo®),meningococcal group A, C, W and Y conjugate vaccine (Menquadfi®),Quadrivalent Influenza Vaccine (recombinant, prepared in cell culture) (Supemtek®)

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