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PYY3-36 and pancreatic polypeptide reduce food intake in an additive manner via distinct hypothalamic dependent pathways in mice.

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      Abstract

      Peptide YY (PYY3-36) and pancreatic polypeptide (PP) potently inhibit food intake in rodents and humans, however, it is unclear whether they have any synergistic/additive interaction in decreasing food intake.

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      Affiliations
      [1 ] Neuroscience Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia; Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
      Journal
      Obesity (Silver Spring)
      Obesity (Silver Spring, Md.)
      1930-739X
      1930-7381
      Dec 2013
      : 21
      : 12
      10.1002/oby.20534 23804428
      Copyright © 2013 The Obesity Society.

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