There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited
cardiomyopathy that is characterized clinically by ventricular arrhythmias and an
increased risk of sudden death and pathologically by fibrofatty replacement of the
myocardium. Soon after the initial description of the disease, investigators and clinicians
caring for patients with ARVD/C recognized a link between exercise and ARVD/C. In
this article, we review the considerable body of epidemiologic data, basic research,
and clinical research supporting the link between exercise and the development and
outcomes of ARVD/C. Based on these data, we now advise that patients with ARVD/C avoid
participation in competitive athletics and limit exercise as much as possible.