Dynamic response of C-type natriuretic peptide and its aminoterminal propeptide (NTproCNP) to growth hormone treatment in children with short stature.

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Abstract

C-type natriuretic peptide (CNP) and its aminoterminal propeptide (NTproCNP) are potential biomarkers of recombinant human growth hormone (rhGH) efficacy. The objective of this study was to describe the pharmacodynamics of plasma CNP and NTproCNP levels in response to rhGH treatment and to identify the optimal time of sampling after starting rhGH.

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Journal

Journal ID (iso-abbrev): Clin Endocrinol (Oxf)

Title: Clinical endocrinology

Publisher: Wiley

ISSN (Electronic): 1365-2265

ISSN (Print): 0300-0664

Publication date (Electronic): Oct 2016

Volume: 85

Issue: 4

Affiliations

[1 ] Nemours Children's Health System, Jacksonville, FL, USA. rolney@nemours.org.

[2 ] Children's Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA, USA.

[3 ] University of Otago, Christchurch, New Zealand.

[4 ] Nemours Children's Health System, Jacksonville, FL, USA.

Article

DOI: 10.1111/cen.13103

PubMed ID: 27177682

SO-VID: 4152bcc7-d3e3-43ad-80f5-0548e4d3d3b2

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