0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Monitored anesthesia care (MAC) sedation: clinical utility of fospropofol

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Fospropofol, a phosphorylated prodrug version of the popular induction agent propofol, is hydrolyzed in vivo to release active propofol, formaldehyde, and phosphate. Pharmacodynamic studies show fospropofol provides clinically useful sedation and EEG/bispectral index suppression while causing significantly less respiratory depression than propofol. Pain at the injection site, a common complaint with propofol, was not reported with fospropofol; the major patient complaint was transitory perianal itching during the drug’s administration. Although many clinicians believe fospropofol can safely be given by a registered nurse, the FDA mandated that fospropofol, like propofol, must be used only in the presence of a trained anesthesia provider.

          Related collections

          Author and article information

          Journal
          Ther Clin Risk Manag
          Therapeutics and Clinical Risk Management
          Therapeutics and Clinical Risk Management
          Dove Medical Press
          1176-6336
          1178-203X
          2009
          2009
          29 December 2009
          : 5
          : 949-959
          Affiliations
          Department of Anesthesiology, Perioperative Management, and Pain Medicine, University of Miami/Miller School of Medicine
          Author notes
          Correspondence: David A Lubarsky Emanuel M Papper Professor and Chair, Department of Anesthesiology, Perioperative Management, and Pain Medicine, University of Miami/Miller School of Medicine, 1611 NW 12th Ave, Miami, FL 33136, USA, Email dlubarsky@ 123456med.miami.edu
          Article
          tcrm-5-949
          2801588
          20057894
          © 2009 Harris et al, publisher and licensee Dove Medical Press Ltd.

          This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

          Categories
          Review

          Medicine

          propofol, fospropofol, monitored anesthesia care

          Comments

          Comment on this article