Contributors
Lijie Ma: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: Visualization
Yan Liu: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: VisualizationRole: Writing – review & editing
Nichole K. Landry: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: Visualization
Tarek M. El-Achkar: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: SupervisionRole: ValidationRole: VisualizationRole: Writing – review
& editing
John C. Lieske: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: SupervisionRole: ValidationRole: VisualizationRole: Writing – review
& editing
Xue-Ru Wu:
ORCID: http://orcid.org/0000-0001-6058-6291
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SoftwareRole:
SupervisionRole: ValidationRole: VisualizationRole: Writing – original draftRole:
Writing – review & editing
Jean-Claude Dussaule: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
16
November
2017
Publication date Collection: 2017
Volume: 12
Issue: 11
Electronic Location Identifier: e0186769
Affiliations
[1
]
Departments of Urology and Pathology, New York University School of Medicine, New
York, New York, United States of America
[2
]
Division of Nephrology, Indiana University School of Medicine and Indianapolis VA,
Indianapolis, Indiana, United States of America
[3
]
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United
States of America
[4
]
Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, New
York, United States of America
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-16637
DOI: 10.1371/journal.pone.0186769
PMC ID: 5690637
PubMed ID: 29145399
SO-VID: 4274e677-5a1f-455c-a7f8-53a5a1299a85
Copyright © © 2017 Ma et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 30
April
2017
Date
accepted
: 7
October
2017
Page count
Figures: 8,
Tables: 1,
Pages: 21
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100000062, National Institute of Diabetes and Digestive and Kidney Diseases;
Award ID: R01DK056903
Award Recipient
:
ORCID: http://orcid.org/0000-0001-6058-6291
Xue-Ru Wu
Funded by: funder-id http://dx.doi.org/10.13039/100000062, National Institute of Diabetes and Digestive and Kidney Diseases;
Award ID: U54DK100227
Award Recipient
:
John C. Lieske
Funded by: funder-id http://dx.doi.org/10.13039/100000738, U.S. Department of Veterans Affairs;
Award ID: 1I01BX002049
Award Recipient
:
ORCID: http://orcid.org/0000-0001-6058-6291
Xue-Ru Wu
This work was supported in part by grants from the United States National Institutes
of Health (R01DK056903), the Mayo Clinic O’Brien Urology Research Center (U54DK100227),
and the Veterans Affairs Office of Research and Development (Biomedical Laboratory
Research and Development Service; 1I01BX002049) and a grant-in-aid from the Goldstein
Fund for Urological Research of the New York University School of Medicine. The funders
had no role in study design, data collection and analysis, decision to publish, or
preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Research and Analysis Methods
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Mouse Models
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Urine
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Urine
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Urine
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Urine
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Renal System
Subject:
Kidneys
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Renal System
Subject:
Kidneys
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Biomarkers
Subject:
Creatinine
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Acids
Subject:
Uric Acid
Subject:
Research and Analysis Methods
Subject:
Histochemistry and Cytochemistry Techniques
Subject:
Immunohistochemistry Techniques
Subject:
Research and Analysis Methods
Subject:
Immunologic Techniques
Subject:
Immunohistochemistry Techniques
Subject:
Research and Analysis Methods
Subject:
Specimen Preparation and Treatment
Subject:
Staining
Subject:
Cytoplasmic Staining
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Apoptosis
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