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      Diagnosis of cypress pollen allergy: in vivo and in vitro standardization of a Juniperus ashei pollen extract.

      1 , , , ,
      Allergy

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          Abstract

          Cypress pollen allergy is a major cause of rhinoconjunctivitis and asthma in the Mediterranean area. The nonstandardized cypress allergen extracts currently available for the diagnosis of cypress allergy have a low level of activity. The search for an active material has led to the selection of Juniperus ashei (Ja) pollen because of its very high cross-reactivity with cypress extracts and its superior allergenic activity. The aim of this study was to characterize in vitro and calibrate in vivo an in-house reference extract (IHRS) of J. ashei pollen and determine the specificity and sensitivity of a standardized Ja extract for the prick test diagnosis of cypress allergy.

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          Author and article information

          Journal
          Allergy
          Allergy
          0105-4538
          0105-4538
          Aug 2003
          : 58
          : 8
          Affiliations
          [1 ] Département Scientifique et Médical, Stallergènes S.A., Antony, France; Aix en Provence, France.
          Article
          247
          12859563
          42c5cbae-c252-4937-8887-772064c38cc3
          History

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