Epigenetic control of trefoil factor family (TFF) peptide expression in human retinoblastoma cell lines.

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Abstract

Recent studies demonstrated that epigenetic mechanisms are involved in the regulation of trefoil factor family (TFF) peptide expression in cancer. In human tissues with endogenous TFF1, TFF2 or TFF3 gene expression, the corresponding promoter is unmethylated and in organs without TFF expression, the promoter of the three genes is highly methylated.

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Journal

Journal ID (iso-abbrev): Cell. Physiol. Biochem.

Title: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Publisher: S. Karger AG

ISSN (Electronic): 1421-9778

ISSN (Print): 1015-8987

Publication date (Electronic): 2014

Volume: 34

Issue: 3

Affiliations

[1 ] University of Duisburg-Essen, Medical Faculty, Institute of Anatomy, Department of Neuroanatomy, Essen, Germany.

Article

Publisher Item ID: 000366316

DOI: 10.1159/000366316

PubMed ID: 25199519

SO-VID: 42f07d0b-bcdc-4a0f-af7a-585f668682dd

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