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      Three-dimensional paper microfluidic devices assembled using the principles of origami.

      Journal of the American Chemical Society
      Colorimetry, Microfluidic Analytical Techniques, instrumentation, methods, Paper, Spectrometry, Fluorescence

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          Abstract

          We report a method, based on the principles of origami (paper folding), for fabricating three-dimensional (3-D) paper microfluidic devices. The entire 3-D device is fabricated on a single sheet of flat paper in a single photolithographic step. It is assembled by simply folding the paper by hand. Following analysis, the device can be unfolded to reveal each layer. The applicability of the device to chemical analysis is demonstrated by colorimetric and fluorescence assays using multilayer microfluidic networks.

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          Author and article information

          Journal
          22004329
          10.1021/ja2071779

          Chemistry
          Colorimetry,Microfluidic Analytical Techniques,instrumentation,methods,Paper,Spectrometry, Fluorescence

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