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      Major depressive disorder induced by prolactinoma--a case report.

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          Abstract

          Prolactinomas, the most common type of pituitary tumor, can induce hyperprolactinemia and cause some psychiatric symptoms, such as anxiety, depression and even psychotic symptoms. However, in previous case reports, no information about estrogen levels was mentioned. Here, we present a 48-year-old female patient who had a recurrent episode of major depressive disorder (MDD) and amenorrhea. Hyperprolactinemia (167 ng/ml), low estrogen (15.31 pg/ml) and a pituitary prolactinoma were found by MRI. After a dopamine agonist (Dostinex) and aripiprazole were prescribed, the patient's depressed mood remitted and her menstruation normalized. The possible mechanism of MDD induced by prolactinoma is discussed.

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          Author and article information

          Journal
          Gen Hosp Psychiatry
          General hospital psychiatry
          1873-7714
          0163-8343
          : 36
          : 1
          Affiliations
          [1 ] Department of Psychiatry, Taipei Veterans General Hospital, Taipei 112, Taiwan.
          [2 ] Department of Psychiatry, Taipei Veterans General Hospital, Taipei 112, Taiwan; Department of Psychiatry, Collage of Medicine, National Yang-Ming University, Taipei 112, Taiwan. Electronic address: ymbi@mail2000.com.tw.
          S0163-8343(13)00015-7
          10.1016/j.genhosppsych.2013.01.010
          24182617
          Copyright © 2014 Elsevier Inc. All rights reserved.

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