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      Renal Phosphate and Calcium Excretory Defects in a Case of Acute Phosphorus Poisoning

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      Nephron

      S. Karger AG

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          Abstract

          A case of acute phosphorus poisoning with hypocalcemia and hypophosphatemia with recovery is presented. The urinary calcium and phosphate excretion data–obtained when significant hypocalcemia and hypophosphatemia were present and considered in relation to the estimated oral intake and creatinine clearance–provided evidence for hypercalciuria and hyperphosphaturia. Other renal abnormalities included very slight aminoaciduria, pyuria, hematuria and proteinuria, transient azotemia, and occasional glycosuria when FBS ranged from 100–117 mg/100 ml in a patient with probable diabetes mellitus. The studies of urinary concentrating and acidifying mechanisms were consistent with preservation of these functions. These observations suggest that disturbance of proximal tubular function particularly may occur in acute phosphorus poisoning.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1966
          1966
          26 November 2008
          : 3
          : 2
          : 123-128
          Affiliations
          Department of Medicine, St. Luke’s Hospital Center, New York City, N.Y.
          Article
          179452 Nephron 1966;3:123–128
          10.1159/000179452
          5922369
          © 1966 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

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