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      A Preliminary Investigation of PVT1 on the Effect and Mechanisms of Hepatocellular Carcinoma: Evidence from Clinical Data, a Meta-Analysis of 840 Cases, and In Vivo Validation.

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          Abstract

          Hepatocellular carcinoma (HCC) remains a difficult problem that significantly affects the survival of the afflicted patients. Accumulating evidence has demonstrated the functions of long non-coding RNA (lncRNA) in HCC. In the present study, we aimed to explore the potential roles of PVT1 in the tumorigenesis and progression of HCC.

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          Author and article information

          Journal
          Cell. Physiol. Biochem.
          Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
          S. Karger AG
          1421-9778
          1015-8987
          2018
          : 47
          : 6
          Affiliations
          [1 ] Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.
          [2 ] Department of Medical Ultrasonics, First Affiliated Hospital of Guangxi Medical University, Nanning, China.
          [3 ] Department of Orthopedics, Shandong Provincial Hospital affiliated to Shandong University, Jinan, China.
          Article
          000491534
          10.1159/000491534
          29975928
          4346c787-c4ce-4050-9a13-4e07d07354f9
          History

          CAM,GEO,Hepatocellular carcinoma,INCENP,MiR-424-5p,Pvt1,TCGA
          CAM, GEO, Hepatocellular carcinoma, INCENP, MiR-424-5p, Pvt1, TCGA

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