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Abstract
Candida auris is an emerging fungal pathogen responsible for nosocomial invasive infection
outbreaks on five continents. Large healthcare-related outbreaks of C. auris infection
and colonization have been reported from different countries. Whole genome sequence
analysis identified strong phylogeographic C. auris clades specific to particular
geographical areas suggesting transmission of particular clades within countries.
However, the mode of transmission within the healthcare environment is not clear and
is likely to be multifactorial. The emergence of C. auris is alarming because this
organism can harbor or develop multidrug resistance. This explains why C. auris infections
are difficult to treat. In addition, difficulties in its identification in the routine
diagnostic laboratory have a significant impact on outbreak detection and management.
This mini-review highlights the available literature on C. auris, with particular
insight into its epidemiology and the problems caused by its antifungal resistance.