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      Clinical Phenotype and Genotype Associations With Improvement in Left Ventricular Function in Dilated Cardiomyopathy.

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          Abstract

          Improvement of left ventricular function (also called left ventricular reverse remodeling [LVRR]) is an important treatment goal in patients with dilated cardiomyopathy (DCM) and hypokinetic non-DCM (HNDC) and is prognostically favorable. We tested whether genetic DCM mutations impact LVRR independent from clinical parameters.

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          Author and article information

          Journal
          Circ Heart Fail
          Circulation. Heart failure
          Ovid Technologies (Wolters Kluwer Health)
          1941-3297
          1941-3289
          November 2018
          : 11
          : 11
          Affiliations
          [1 ] Department of Cardiology, Maastricht University Medical Centre, the Netherlands (J.A.J.V., M.R.H., S.S.-v.W., J.J.M., H.-P.B.-L.R., S.R.B.H.).
          [2 ] Department of Clinical Genetics, Maastricht University Medical Centre, the Netherlands (J.A.J.V., P.W., Y.A.A., A.v.d.W., I.P.C.K., H.G.B.).
          [3 ] Department of Human Genetics, Donders Center for Neuroscience, Radboudumc, Nijmegen, the Netherlands (H.G.B.).
          [4 ] Department of Cardiovascular Research, University of Leuven, Belgium (S.R.B.H.).
          [5 ] Netherlands Heart Institute, Utrecht (S.R.B.H.).
          Article
          10.1161/CIRCHEARTFAILURE.118.005220
          30571196
          43a0316f-7dd7-4c08-a67d-bf9ab331658e
          History

          cardiomyopathy, dilated,therapeutics,ventricular remodeling,humans

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