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MiR-20b Displays Tumor-Suppressor Functions in Papillary Thyroid Carcinoma by Regulating the MAPK/ERK Signaling Pathway.
Shubin Hong
1 ,
Shuang Yu
1 ,
Jin Li
2 ,
Yali Yin
1 ,
Yujie Liu
3 ,
Quan Zhang
4 ,
Hongyu Guan
1 ,
Yanbing Li
1 ,
Haipeng Xiao
1
Dec 2016
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Abstract
MicroRNAs (miRNAs) are endogenous, small, non-coding RNAs that play important roles in multiple biological processes. MiR-20b has been reported to be dysregulated in papillary thyroid carcinoma (PTC). However, the functional roles are still largely unknown. This study aimed to investigate the biological functions and the underlying molecular mechanisms of miR-20b in PTC.