Blog
About

2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      [Recent advances on TRP channels].

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The transient receptor potential (TRP) superfamily of ion channels comprises 28 members of cation-selective ion channels in Mammalian. On the basis of amino acid sequence homology, TRP channels are grouped into six subfamilies (TRPC, TRPV, TRPM, TRPA, TRPP, and TRPML). All TRP channels have six predicted transmembrane segments in structure, and different selection for calcium and sodium in permeance. TRP channels are also widespread and activated by multiple stimuli. Meanwhile, as the sensor to the changes in cellular local environments, TRP channels have diverse functions, including thermal, mechanical and taste sensing, as well as maintaining ion homeostasis.

          Related collections

          Author and article information

          Journal
          Sheng Li Ke Xue Jin Zhan
          Sheng li ke xue jin zhan [Progress in physiology]
          0559-7765
          0559-7765
          Jan 2008
          : 39
          : 1
          Affiliations
          [1 ] Department of Pharmacology, Institute of Materia Media, Chinese Academy of Medical Sciences, Beijing.
          18357684

          Comments

          Comment on this article