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      Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Novel Meningoencephalomyelitis.

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          Abstract

          A novel astrocytic autoantibody has been identified as a biomarker of a relapsing autoimmune meningoencephalomyelitis that is immunotherapy responsive. Seropositivity distinguishes autoimmune glial fibrillary acidic protein (GFAP) meningoencephalomyelitis from disorders commonly considered in the differential diagnosis.

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          Author and article information

          Journal
          JAMA Neurol
          JAMA neurology
          American Medical Association (AMA)
          2168-6157
          2168-6149
          Nov 01 2016
          : 73
          : 11
          Affiliations
          [1 ] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
          [2 ] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota2Department of Neurology, Mayo Clinic, Rochester, Minnesota.
          [3 ] Department of Neurology, Mayo Clinic, Rochester, Minnesota.
          [4 ] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota2Department of Neurology, Mayo Clinic, Rochester, Minnesota3Department of Immunology, Mayo Clinic, Rochester, Minnesota.
          Article
          2548268
          10.1001/jamaneurol.2016.2549
          27618707

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