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      Monitoring the effects of anti-angiogenesis on the radiation sensitivity of pancreatic cancer xenografts using dynamic contrast-enhanced computed tomography.

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          Abstract

          To image the intratumor vascular physiological status of pancreatic tumors xenografts and their response to anti-angiogenic therapy using dynamic contrast-enhanced computed tomography (DCE-CT), and to identify parameters of vascular physiology associated with tumor x-ray sensitivity after anti-angiogenic therapy.

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          Author and article information

          Journal
          Int. J. Radiat. Oncol. Biol. Phys.
          International journal of radiation oncology, biology, physics
          1879-355X
          0360-3016
          Feb 1 2014
          : 88
          : 2
          Affiliations
          [1 ] School of Health Sciences, Purdue University, West Lafayette, Indiana; Radiation Oncology, University of Washington, Seattle, Washington.
          [2 ] Radiation Oncology, University of California-Los Angeles, Los Angeles, California.
          [3 ] Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
          [4 ] School of Health Sciences, Purdue University, West Lafayette, Indiana; Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: kstantz@purdue.edu.
          Article
          S0360-3016(13)03304-X NIHMS548348
          10.1016/j.ijrobp.2013.11.002
          3931463
          24411612
          44287515-478f-4615-b8fb-9fee6db54ac7
          Copyright © 2014 Elsevier Inc. All rights reserved.
          History

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