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      The Importance of Creatine Kinase Determination in Identifying Acute Myocardial Infarction among Patients Complaining of Chest Pain in an Emergency Room

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          The contribution of serum creatine kinase (CK) levels to the diagnosis of acute myocardial infarction (AMI) in an emergency room was studied in 252 patients presenting with chest pain. Thirty percent were ultimately diagnosed as having AMI. The electrocardiogram (ECG) identified 66% of patients with AMI who were evaluated within 4 h of onset of symptoms; while CK serum levels were elevated in only 9%. Among patients evaluated more than 4 h after the onset of symptoms, the ECG was helpful in diagnosing AMI in only 36.6%, while serum CK levels were high in 63.4%. CK testing added significantly to the diagnosis of AMI in patients already studied by ECG. We suggest that determination of serum CK levels in the emergency room is of value in the evaluation of patients complaining of chest pain 4 or more hours after the onset of symptoms.

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          Author and article information

          S. Karger AG
          11 November 2008
          : 74
          : 2
          : 100-110
          Department of Medicine D, The Tel Aviv Medical Center, Ichilov Hospital, and Sackler School of Medicine, Tel Aviv University; Department of Economics, Bar Ilan University, and The Faculty of Statistics, Tel Aviv University, Israel
          174183 Cardiology 1987;74:100–110
          © 1987 S. Karger AG, Basel

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          Pages: 11
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